She went into the French Open among the favorites, following the sudden retirement of four-time champion Justine Henin. However, she lost in the semifinals, to eventual champion Venus Williams and ended the year as world no.However, she lost to compatriot and eventual champion Ivanovic after leading by a break in the third set. However, she did reach a new career-high of world no. The Olympic Committee of Serbia declared her the best sportswoman for the second year in a row.In the deciding doubles match, she partnered with Ana Ivanovic but fell to Kuznetsova and Kleybanova.Her next scheduled tournament was the Dubai Tennis Championships where she lost to Vera Zvonareva in the third round.
In her second year-end championship semifinal she lost to Venus Williams in three sets. In her first match, she rallied from 4—6, 1—4 down to defeat Alisa Kleybanovathen defeated reigning French Open Champion Svetlana Kuznetsova.She lost to 16th-seeded Marion Bartoli in the fourth round.After the match, she conceded that she has been struggling with her confidence, saying "I need a lot of work.In her opening match she lost to Kuznetsova despite having a match point in the third set.She began the year at the Shenzhen Open as the top seed and defending champion, where she reached the quarterfinal before losing to Alison Riske.